Disease: Aplasia Cutis Congenita
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
VCAN P13611 versican Extracellular structure 1.00 0.497 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SPEN Q96T58 spen family transcriptional repressor 1.00 0.644 0.654
SOX4 Q06945 SRY-box transcription factor 4 Transcription factor 0.93 0.489 0.808
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PRKD1 Q15139 protein kinase D1 Kinase 6.6E-07 0.531 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PLAG1 Q6DJT9 PLAG1 zinc finger Transcription factor 1.00 0.493 0.808
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PGR P06401 progesterone receptor Nuclear receptor 5.1E-02 0.426 0.885
PCNA P12004 proliferating cell nuclear antigen Nucleic acid binding 0.98 0.382 0.846
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MARCKS P29966 myristoylated alanine rich protein kinase C substrate 0.33 0.559 0.769
LEF1 Q9UJU2 lymphoid enhancer binding factor 1 1.00 0.486 0.769
KRT15 P19012 keratin 15 2.4E-16 0.659 0.538
JAG1 P78504 jagged canonical Notch ligand 1 1.00 0.429 0.808
ITGB4 P16144 integrin subunit beta 4 Receptor 9.5E-19 0.525 0.731